SCAPIS
| Reference number | |
| Coordinator | HJÄRT-LUNGFONDEN SV NAT FÖREN MOT HJ O LUNGSJUKD - Hjärt-Lungfonden |
| Funding from Vinnova | SEK 20 500 000 |
| Project duration | December 2012 - June 2016 |
| Status | Completed |
Important results from the project
The aims of the Swedish CArdioPulmonary bioImage Study (SCAPIS) are (1) to use advanced imaging technologies of atherosclerosis in the coronary and carotid arteries together with information obtained by proteomics/metabolomics/genomics technologies to improve risk prediction for cardiovascular disease (CVD), leading to a better- targeted intensive risk factor interventions, saving lives and medical costs
Expected long term effects
SCAPIS will build a nationwide, open-access, population-based cohort for the study of CVD and COPD. SCAPIS will recruit and investigate 30,000 men and women aged 50 to 65 years with detailed imaging and functional analyses of the cardiovascular and pulmonary systems. Data will be collected at six Swedish universities (Uppsala, Umeå, Linköping, Gothenburg, Karolinska Institutet and Lund). Biobanked blood and DNA will be analyzed at SciLifeLab. Follow-up will be done through national registries
Approach and implementation
SCAPIS will benefit the health care system both in the short- and the long-term. In the short-term, SCAPIS will improve: (1) understanding of new risk factor patterns and their aggregation in certain areas of society, enabling better- targeted prevention efforts; (2) clinical evaluation and understanding of subclinical forms of disease; and (3) risk stratification based on information obtained using modern imaging and omics techniques. Long-term effects include: (1) discovery of new mechanisms of diseases, leading to new treatments; (2) health economic understanding