Control and automation of industrial biological processes

Important results from the project

The project has developed solutions for increased productivity in the biotechnology and biopharmaceutical industry through increased optimization and automation. The project focused on the two most important steps in a biotechnological process, the fed-batch reactor and industrial chromatographic separation. A technique for optimal dosing in fed-batch cultivation has been verified industrially. Technology for advanced separation process management has been developed, which has also been tested entire downstream processes with successful results.

Expected long term effects

Technique for optimal dosing in fed batch cultivation has been verified industrially with very successful results. The technology is used by the project partners. Technology for advanced control of separation steps for individual steps and entire downstream processes has attracted much interest. It has managed to allocate more funding through several new spin-off projects, including the Smart Mini Factory concept. Research, development and innovation continue in this area.

Approach and implementation

The project consisted of three work packages that had clear contact points with each other but was in different phases of development. WP1 was in a clear implementation phase compared with WP3 that was in an early definition phase. All work packages had great industrial interest and major industrial commitments, verified by the increased industrial co-financing. At the same time, a developed concept within the project has required both more resources and new partners, which has resulted in new spin-off projects starting, and thus the original project has been by-passed.