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A pharmacological treatment for stroke recovery

Reference number
Coordinator Sinntaxis AB
Funding from Vinnova SEK 300 000
Project duration June 2018 - June 2019
Status Completed
Venture Innovative Startups
Call Innovative Startups step 1 spring 2018

Important results from the project

The aim of the project was to initiate the development of a drug that improves post-stroke recovery. Treatment efficacy studies have been carried out with a molecule ready for the clinic that have shown excellent functional recovery and the company has decided to continue with this substance. Meetings with Key Opinion Leaders have been conducted and valuable information has been gathered in preparation of the protocol for the upcoming clinical Proof-of Concept study. Furthermore, a long-term patent strategy has been developed in accordance with the objective of the project.

Expected long term effects

Thanks to the result of the project, Sinntaxis has the rights to a drug candidate ready for clinic with excellent animal experimental data for functional recovery after stroke. This means that the upcoming clinical development work is shortened and the risk is significantly reduced for the project. The meetings with Key Opinion Leaders have provided valuable input for the design of the planned clinical Proof-of-Concept study. The development of a patent strategy has further strengthened the project´s position and increased its value.

Approach and implementation

After initial analysis of the three available molecules, one has been selected and tested in a series of studies in validated mouse models with excellent results for functional recovery. Meetings have been held with Key Opinion Leaders, where the clinical development plan has been discussed and provided valuable input. Patent issues related to the selected drug candidate were investigated together with the company´s patent attorneys and a patent strategy comprising patent application, know-how and data protection that follows from future clinical studies has been developed.

External links

The project description has been provided by the project members themselves and the text has not been looked at by our editors.

Last updated 20 January 2020

Reference number 2018-01136