A pharmacological treatment for stroke recovery
Reference number | |
Coordinator | Sinntaxis AB |
Funding from Vinnova | SEK 300 000 |
Project duration | June 2018 - June 2019 |
Status | Completed |
Venture | Innovative Startups |
Call | Innovative Startups step 1 spring 2018 |
Important results from the project
The aim of the project was to initiate the development of a drug that improves post-stroke recovery. Treatment efficacy studies have been carried out with a molecule ready for the clinic that have shown excellent functional recovery and the company has decided to continue with this substance. Meetings with Key Opinion Leaders have been conducted and valuable information has been gathered in preparation of the protocol for the upcoming clinical Proof-of Concept study. Furthermore, a long-term patent strategy has been developed in accordance with the objective of the project.
Expected long term effects
Thanks to the result of the project, Sinntaxis has the rights to a drug candidate ready for clinic with excellent animal experimental data for functional recovery after stroke. This means that the upcoming clinical development work is shortened and the risk is significantly reduced for the project. The meetings with Key Opinion Leaders have provided valuable input for the design of the planned clinical Proof-of-Concept study. The development of a patent strategy has further strengthened the project´s position and increased its value.
Approach and implementation
After initial analysis of the three available molecules, one has been selected and tested in a series of studies in validated mouse models with excellent results for functional recovery. Meetings have been held with Key Opinion Leaders, where the clinical development plan has been discussed and provided valuable input. Patent issues related to the selected drug candidate were investigated together with the company´s patent attorneys and a patent strategy comprising patent application, know-how and data protection that follows from future clinical studies has been developed.